Hitoyoshi
Yasuo (Yas),
studied for his PhD thesis
in the
laboratory of Nori Satoh (1991-1996),
where he carried out one of the first molecular studies in ascidians,
analysing
the ascidian Brachyury gene,
called As-T, in order to
address the molecular basis of notochord differentiation.
For his
post-doctoral study, he decided to work on a vertebrate model, Xenopus
laevis. He joined
the
laboratory of Patrick
Lemaire, IBDM, Marseille,
France (1996-2000), where he was involved in projects addressing;
endoderm determination, mesoderm induction and regionalisation of the
dorsal mesoderm. Yas was recruited into the French research
organisation,
the CNRS, in October 2001 and, with a support of the CNRS young
investigator grant (ATIP), he created his own research group here in
Villefranche-sur-mer
in the Unité de Biologie du Developpement.
Selected
references from
Yas's PhD and postdoc (latest first):
for more recent publications see our group publication list
Yasuo, H and
Lemaire, P. (2001). Role of
Goosecoid, Xnot and Wnt
antagonists in the maintenance of the notochord genetic programme in Xenopus gastrulae. Development 128,
3783-93.
PubMed
Carballada*,
R., Yasuo*,
H. and Lemaire,
P. (2001). Phosphatidylinositol-3 kinase acts in parallel to the ERK
MAP kinase
in the FGF pathway during Xenopus mesoderm
induction.
Development 128, 35-44. *equal contribution.
PubMed
Yasuo, H and
Lemaire, P. (1999). A two-step
model for the fate
determination of presumptive endodermal blastomeres in Xenopus embryos. Curr. Biol. 9, 869-79.
PubMed
Yasuo, H and Satoh,
N. (1998). Conservation
of the developmental
role of Brachyury in notochord formation in a urochordate, the ascidian Halocynthia roretzi. Dev. Biol. 200,
158-70. PubMed
Nakatani,
Y., Yasuo,
H., Satoh, N and
Nishida, H. (1996). Basic fibroblast growth factor induces notochord
formation
and the expression of As-T, a Brachyury homolog,
during ascidian
embryogenesis. Development 122,
2023-31. PubMed
Yasuo, H and Satoh,
N. (1993) Function of
vertebrate T gene. Nature 364,
582-3.
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